Bioinspired total synthesis of katsumadain A by organocatalytic enantioselective 1,4-conjugate addition

نویسندگان

  • Yongguang Wang
  • Ruiyang Bao
  • Shengdian Huang
  • Yefeng Tang
چکیده

Katsumadain A, a naturally occurring influenza virus neuraminidase (NA) inhibitor, was synthesized by using a bioinspired, organocatalytic enantioselective 1,4-conjugate addition of styryl-2-pyranone with cinnamaldehyde, followed by a tandem Horner-Wadsworth-Emmons/oxa Michael addition.

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عنوان ژورنال:

دوره 9  شماره 

صفحات  -

تاریخ انتشار 2013